83370
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83370
Fluka
Quercetin dihydrate
BioChemika, ≥98.0% (HPLC)
| Synonym: | 3,3′,4′,5,7-Pentahydroxyflavone dihydrate, 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate |
| CAS Number: | 6151-25-3 |
| Linear Formula: | C15H10O7 · 2H2O |
| Molecular Weight: | 338.27 |
| Colour Index Number: | 75670 |
| Beilstein Registry Number: | 317313 |
| EC Number: | 204-187-1 |
| MDL number: | MFCD00149487 |
Description
| Other Notes | Inhibitor of mitochondrial ATPase1; Potent phosphodiesterase inhibitor2; Mutagenic activity in bacteria3 |
| Biochem/physiol Actions | Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. |
Properties
| product line | BioChemika |
| assay | ≥98.0% (HPLC) |
| ign. residue | ≤0.3% |
| mp | >300 °C(lit.) |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | LK8950000 |
References
| Cited Reference | 1. D.R. Lang, E. Racker Biochim. Biophys. Acta 333, 180, (1974) |
2. A. Beretz et al. Experientia 34, 1054, (1978) Abstract | |
| 3. L.F. Bjeldanes, G.W. Chang Science 197, 577, (1977) Abstract | |
| Merck | Merck 13,8122 |
| Beilstein | Beil. 18,V,5,494 |
| reference | Aldrich MSDS 1, 1577:B / Corp MSDS 1 (2), 3019:D / FT-IR 2 (2), 2509:C / FT-IR 1 (2), 96:B / FT-NMR 1 (2), 920:B / IR-Spectra (3), 906:F / IR-Spectra (2), 793:D / NMR-Reference 2 (2), 98:D / RegBook 1 (2), 1697:K / Sigma FT-IR 1 (2), 877:C / Structure Index 1, 270:D:1 |
